Protein_Domain

Part:BBa_K4803006

Designed by: Kotaro MURAI   Group: iGEM23_UTokyo   (2023-10-10)


CD28 transmembrane domain

This Part is the CD28-derived transmembrane domain (CD28TMD). This domain allows transmembrane proteins to anchor the cell membrane.

This Part is adapted from the transmembrane domain of a protein used in the MESA (Modular Extracellular Sensor Architecture) system described in [1].

In UTokyo2023 project, this part is commonly used as the transmembrane domain of the protein that makes up the MESA system [1].


Sequence and Features


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    COMPATIBLE WITH RFC[25]
  • 1000
    COMPATIBLE WITH RFC[1000]

Reference

[1] Daringer, N. M., Dudek, R. M., Schwarz, K. A., & Leonard, J. N. (2014). Modular extracellular sensor architecture for engineering mammalian cell-based devices. ACS synthetic biology, 3(12), 892-902. https://doi.org/10.1021/sb400128g


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